Cenforce 200 mg, like other Sildenafil-based medications, works by inhibiting the enzyme phosphodiesterase type 5 (PDE5). This inhibition leads to an increase in cyclic GMP (cGMP) levels, which causes the blood vessels in the penis to relax and dilate, allowing more blood to flow into the penis during sexual arousal. This increased blood flow helps in achieving and maintaining a firm erection.