Cenforce 50 mg works by inhibiting the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP). cGMP helps relax the blood vessels in the penis, leading to increased blood flow. By inhibiting PDE5, Cenforce helps maintain higher levels of cGMP, promoting better blood flow to the penis and making it easier for men to achieve and sustain an erection during sexual activity.